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During metaphase I of meiosis the homologous pairs of chromosomes align along the equator. The orientation of the chromosomes is random. This means that when the pairs of homologous chromosomes move to opposite poles during anaphase I, either chromosome can end up at either pole.

This depends on which way the pair is facing (occurs randomly). Also, which ever way the pair is facing does not affect which way the other homologous chromosome pairs are facing. This is known as idenpendent orientation and forms the basis of Mendel’s law of independent assortment.

Unlinked genes are found on different chromosomes so when the homologous chromosome pairs seperate it allows the formation of daughter cells with random assortemnets of chromosomes and alleles.

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